What is Horizon Carrier Screening?
The Horizon carrier screen is a simple test that looks at your genes to see if you are a carrier for specific autosomal recessive and X-linked genetic conditions. It is common for people to be carriers of at least one genetic condition. Carriers are usually healthy; however, they have a risk of passing on a genetic condition to their children. Horizon can provide valuable information to you about your carrier status before or during pregnancy.
Horizon™ screens your patients to determine their carrier status for up to 274 autosomal recessive and X-linked genetic conditions. Many of these conditions are early onset, while some conditions develop later in life. Conditions have been carefully selected to be appropriate for your unique mix of patients.
Diseases We Screen
Horizon screens for up to 274 autosomal recessive and X-linked genetic conditions. Patients can be screened for all of these conditions or a select few based on their ethnic background and their physician’s recommendation.
Who should have Horizon carrier screening?
Anyone who is pregnant or planning a pregnancy can have Horizon carrier screening. Egg or sperm donors may also have carrier screening. Ask your doctor or genetic counselor if Horizon carrier screening is right for you. Please note this testing is not available to minors in some cases. Horizon carrier screening for X-linked disorders is limited to female patients.
When should I have Horizon carrier screening?
Horizon can be done before or during pregnancy. Some people may want to have more information about the chance to have a baby with a genetic disease before pregnancy. Others may have screening during a pregnancy.
What are the benefits of having Horizon carrier screening?
Horizon can help you and your partner learn about the chance to have a child with a genetic disease before or during pregnancy. Many people do not know they are a carrier for an inherited genetic disease until they have an affected child. While there is no test that can screen for all possible genetic diseases or birth defects, genetic carrier screening can give you information to make reproductive choices that are right for you and your family.
Do I need to have carrier screening more than once?
Carrier screening is usually done once as your carrier status for a specific condition typically does not change. Depending on what you have been screened for in the past, your doctor or genetic counselor may recommend additional carrier screening for more conditions. So, it is possible to have carrier screening more than once. Ask your doctor or genetic counselor to find out what’s best for you.
Does Natera provide assistance to patients who have positive Horizon results?
Yes, a 30 minute information session with a Natera genetic counselor is available to patients to discuss carrier screening results. Your patients may call 650-249-9090 or visit Natera's Patient Portal to set up a complimentary phone appointment with a Natera genetic counselor.
How can I contact a Natera genetic counselor if I have questions about a result?
Natera’s genetic counselors are available to answer questions about Horizon carrier screening Monday through Friday, 6 AM to 5 PM Pacific Time, excluding holidays. Please call 650-249-9092 and ask to speak with the on-call genetic counselor. You may also email email@example.com with questions.
How do I begin offering Horizon in my practice?
How do I order more kits?
You can order more kits in several ways.
- Email firstname.lastname@example.org and tell them how many kits you want and when you would like them
- Tell your local clinical field specialist
- Log into Natera Connect, choose “order collection kits”, fill out the empty fields and click "submit"
Learn About Inheritance and Reproductive Options
The Knowledge Center provides an overview of how autosomal recessive and X-linked genetic conditions are passed on in families. This section also discusses reproductive options for carriers at different points in their reproductive journeys including pre-pregnancy and during pregnancy.
Access Webinars, Videos, and Screening Guidelines
The Knowledge Center provides access to educational content such as webinars, product videos, white papers, and screening guidelines from ACOG and ACMG.